英语翻译RNA recognition by the embryonic cell fatedeterminant an
来源:学生作业帮 编辑:作业帮 分类:英语作业 时间:2024/05/13 15:54:40
英语翻译
RNA recognition by the embryonic cell fatedeterminant and germline totipotency factor MEX-3
Renewal of totipotent stem cells in the germline and cellular differentiation during early embryogenesis rely upon posttranscriptional regulatory mechanisms.
However,the nucleotide sequence specificity and requirements of MEX-3 mRNA recognition remain unclear.
Only a few candidate regulatory targets have been identified,and the full extent of the network of MEX-3 targets is not known.
Here,we define the consensus sequence required for MEX-3 RNA recognition and demonstrate that this element is required for MEX-3 dependent regulation of gene expression in live worms.
Based on this work,we identify several candidate MEX-3 targets that help explain its dual role in regulating germline stem cell totipotency and embryonic cell fate specification.
RNA recognition by the embryonic cell fatedeterminant and germline totipotency factor MEX-3
Renewal of totipotent stem cells in the germline and cellular differentiation during early embryogenesis rely upon posttranscriptional regulatory mechanisms.
However,the nucleotide sequence specificity and requirements of MEX-3 mRNA recognition remain unclear.
Only a few candidate regulatory targets have been identified,and the full extent of the network of MEX-3 targets is not known.
Here,we define the consensus sequence required for MEX-3 RNA recognition and demonstrate that this element is required for MEX-3 dependent regulation of gene expression in live worms.
Based on this work,we identify several candidate MEX-3 targets that help explain its dual role in regulating germline stem cell totipotency and embryonic cell fate specification.
RNA的识别由胚胎细胞和生殖细胞全能性因素fatedeterminant墨西哥- 3
重建中的生殖细胞全能性干细胞和细胞分化的早期胚胎发育过程中依赖转录后调节机制.
不过,核苷酸序列特异性和墨西哥- 3 mRNA的识别要求仍然不清楚.
只有少数候选人监管的目标已经确定,以及对墨西哥3目标网络充分的程度尚不清楚.
在这里,我们定义的共识序列墨西哥- 3 RNA的识别要求,并显示此元素是墨西哥- 3基因的表达调控依赖于生活蠕虫需要.
在此基础上,我们确定了几个候选人墨西哥- 3的目标,有助于解释在调节生殖细胞和胚胎干细胞的全能性细胞命运规范的双重作用.
重建中的生殖细胞全能性干细胞和细胞分化的早期胚胎发育过程中依赖转录后调节机制.
不过,核苷酸序列特异性和墨西哥- 3 mRNA的识别要求仍然不清楚.
只有少数候选人监管的目标已经确定,以及对墨西哥3目标网络充分的程度尚不清楚.
在这里,我们定义的共识序列墨西哥- 3 RNA的识别要求,并显示此元素是墨西哥- 3基因的表达调控依赖于生活蠕虫需要.
在此基础上,我们确定了几个候选人墨西哥- 3的目标,有助于解释在调节生殖细胞和胚胎干细胞的全能性细胞命运规范的双重作用.
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