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英语翻译3.7.Anti-tumor activity of ARP in vitroIn this study,the

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英语翻译
3.7.Anti-tumor activity of ARP in vitro
In this study,the anti-tumor activity of ARP against two kinds of
human solid cancer cell lines,HEP-G2 and HCT-22,was investigated
in vitro.In Fig.6,ARP significantly inhibited the proliferation
of HEP-G2 cells (p < 0.05) at the concentrations ranging from 50 to
400 lg/ml.The tendency of anti-tumor effect was displayed in a
concentration-dependent manner.At the maximum concentration
of 400 lg/ml,ARP had the maximum inhibition ratio of 54.3 ± 4.7%.
Meanwhile,the proliferation of HCT-22 was significantly suppressed
at the concentration of 200 lg/ml,with the ratio of 60.2 ± 3.6%.The anti-tumor activity of the polysaccharide was usually believed to be a consequence of the stimulation of the cellmediated immune response (Borchers,Keen,& Gershwin,2004; Ooi & Liu,2000; Sullivan,Smith,& Rowan,2006).For instance,immunostimulatory activities were found in the polysaccharides from Polyporus albicans,Grifola frondosa,Pleurotus ostreatus,etc.,
which suggested that immunostimulatory effects might be the
main mechanism for the anti-tumor activities of polysaccharides
(Cui et al.,2007; Sarangi,Ghosh,Bhutia,Mallick,& Maiti,2006;
Sun et al.,2008).But some polysaccharides,such as polysaccharides
from Angelica sinensis (Cao et al.,2006) and Poria cocos
(Huang,Jin,Zhang,Cheung,& Kennedy,2007),could directly inhibit
the proliferation of cancer cell in vitro.From above,we can draw a conclusion that ARP,obtained by the optimum extraction technology through orthogonal experiment methods,has enormous potential for use in medicine against both pathogens and cancer.
3.7 .抗肿瘤活性的体外ARP协议
在这项研究中,抗肿瘤活性的ARP协议对二种
人类固体肿瘤细胞株,株Hep - G2和红细胞压积22 ,进行了调查
体外.图.6 ,ARP协议的增殖具有显着的抑制作用
喉癌Hep - G2期细胞( P “ 0.05 ) ,在浓度为50至
400 LG电子/毫升.的倾向,抗肿瘤作用是显示在一个
浓度依赖性.在最高浓度
400 LG电子/毫升,ARP协议的最大抑制率54.3 ± 4.7 % .
同时,红细胞压积的扩散- 22显着抑制
在浓度为200 LG电子/毫升,其比率为60.2 ± 3.6 % .抗肿瘤活性的多糖,通常认为是一种后果刺激cellmediated免疫反应(博彻斯,基恩和格什温,2004年;图为与刘,2000年;沙利文,史密斯,与罗文,2006年) .例如,免疫活动中发现的白色多孔菌多糖,灰树花,平菇等,
这表明,免疫效果可能是
主要机制的抗肿瘤活性的多糖
(崔天凯等.,2007 ;塞兰奇,戈什,Bhutia ,Mallick ,与梅蒂,2006 ;
孙等人.,2008 ) .但是,一些多糖,如多糖
当归(曹等人.,2006年)和茯苓
(黄,金,张长,与肯尼迪,2007年) ,可直接抑制
扩散的癌细胞在vitro.From如上所述,我们可以得出结论,ARP协议,获得了最佳提取技术,通过正交实验方法,具有巨大的潜力,用于医学打击病原体和癌症.