作业帮我有一些专业英语翻译方面的问题，以前一直求助你们团里的andychewbj但是最近他不接受求助了我来求助你们
来源：学生作业帮 编辑：作业帮 分类：综合作业 时间：2024/05/11 20:11:54
我有一些专业英语翻译方面的问题，以前一直求助你们团里的andychewbj但是最近他不接受求助了我来求助你们
希望你们团里的其他人不要输给他，给我一个最好的答案噢，谢谢了，文章有点难，也很长，当然分我也不会少，先给150，好的话一定追加！谢谢各位了，翻译成中文就好
Moreover, because of their higher intrinsic efficacy,
enkephalins need to occupy fewer opioid receptors than
morphine to give the same pharmacological responses
Moreover, it has been demonstrated
that inhaled NEP-inhibitor, thiorphan, failed to
potentiate allergen-induced airway responses in asthma
The continued development of more effective and predictable
methods for pain control is a process that combines the bestefforts of basic and clinical scientists. Numerous studies have
expanded the understanding of pain by focusing on the key
role that receptors, signal transduction pathways, and genes
play in mediating the response to inflammation or nerve
injury. This has led to the identification of new targets for
analgesic drug development. However, until now, the new
strategies developed lead to drugs that are more active in
animal models than in clinical trials , or are responsible of
side effects。
Pain has traditionally been viewed as a pure sensory experience
arising from physical injury or other pathology (cancer,
diabetes, AIDS). However, it is now well accepted that psychological
and behavioral factors play a key role in the chronic
pain experience。 Thus, modifying theconcentration of endogenous opioid peptides by use of peptidase
inhibitors may be a promising new approach in the treatment
of pain, and in chronic pain, owing to the
antidepressant-like properties of the dual inhibitors recently
confirmed with RB-101. Modulation of the concentrations of
peptide effectors have already been used successfully in the
case of angiotensin-converting enzyme inhibitors and has preceded
the clinical use of angiotensin II receptor antagonists.
Moreover, it is interesting to notice that repeated administration
of high doses of acetorphan does not induce side effects,
even in children . As reported several years ago, coadministration
by the intrathecal route of thiorphan (NEP inhibitor)
and bestatin (APN inhibitor) elicited potent,
reproducible and long-lasting analgesia in cancer patients 。
希望你们团里的其他人不要输给他，给我一个最好的答案噢，谢谢了，文章有点难，也很长，当然分我也不会少，先给150，好的话一定追加！谢谢各位了，翻译成中文就好
Moreover, because of their higher intrinsic efficacy,
enkephalins need to occupy fewer opioid receptors than
morphine to give the same pharmacological responses
Moreover, it has been demonstrated
that inhaled NEP-inhibitor, thiorphan, failed to
potentiate allergen-induced airway responses in asthma
The continued development of more effective and predictable
methods for pain control is a process that combines the bestefforts of basic and clinical scientists. Numerous studies have
expanded the understanding of pain by focusing on the key
role that receptors, signal transduction pathways, and genes
play in mediating the response to inflammation or nerve
injury. This has led to the identification of new targets for
analgesic drug development. However, until now, the new
strategies developed lead to drugs that are more active in
animal models than in clinical trials , or are responsible of
side effects。
Pain has traditionally been viewed as a pure sensory experience
arising from physical injury or other pathology (cancer,
diabetes, AIDS). However, it is now well accepted that psychological
and behavioral factors play a key role in the chronic
pain experience。 Thus, modifying theconcentration of endogenous opioid peptides by use of peptidase
inhibitors may be a promising new approach in the treatment
of pain, and in chronic pain, owing to the
antidepressant-like properties of the dual inhibitors recently
confirmed with RB-101. Modulation of the concentrations of
peptide effectors have already been used successfully in the
case of angiotensin-converting enzyme inhibitors and has preceded
the clinical use of angiotensin II receptor antagonists.
Moreover, it is interesting to notice that repeated administration
of high doses of acetorphan does not induce side effects,
even in children . As reported several years ago, coadministration
by the intrathecal route of thiorphan (NEP inhibitor)
and bestatin (APN inhibitor) elicited potent,
reproducible and long-lasting analgesia in cancer patients 。
翻译您的文章很吃力，所以有时懒得动！！
Moreover, because of their higher intrinsic efficacy, enkephalins need to occupy fewer opioid receptors than morphine to give the same pharmacological responses Moreover, it has been demonstrated that inhaled NEP-inhibitor, thiorphan, failed to potentiate allergen-induced airway responses in asthma
此外，由于拥有较高的固有活性，脑啡肽比吗啡需要占用较少的鸦片受体就能给予相同的药理反应。而且已被证明，吸入脑啡肽酶抑制剂，赛奥芬，对于哮喘的过敏原诱发的气管反应效能没有增强。
The continued development of more effective and predictable methods for pain control is a process that combines the best efforts of basic and clinical scientists. Numerous studies have expanded the understanding of pain by focusing on the key role that receptors, signal transduction pathways, and genes play in mediating the response to inflammation or nerve injury. This has led to the identification of new targets for analgesic drug development. However, until now, the new strategies developed lead to drugs that are more active in animal models than in clinical trials , or are responsible of side effects.
持续发展更多行之有效及可预见性的疼痛控制方法，是将基础与临床科学家们殚精竭虑的成果组合一起的过程。许多研究把焦点集中于受体、信号转导途径和基因对炎症或神经损伤的介质反应的重要作用，对疼痛已有进一步的了解。这导致止痛药物的发展有了新的目标。然而，迄今新策略所发展出来的药物，在动物身上要比临床试验更有效或是有副作用。
Pain has traditionally been viewed as a pure sensory experience arising from physical injury or other pathology (cancer, diabetes, AIDS). However, it is now well accepted that psychological and behavioral factors play a key role in the chronic pain experience。 Thus, modifying the concentration of endogenous opioid peptides by use of peptidase inhibitors may be a promising new approach in the treatment of pain, and in chronic pain, owing to the antidepressant-like properties of the dual inhibitors recently confirmed with RB-101.
传统观念认为疼痛是身体受伤或其他病变（如癌症、糖尿病、艾滋病）所引起的一种纯粹的感官体验。不过，心理与行为因素对长期疼痛所发挥的重要作用如今已被广泛接受。鉴于最近通过RB-101确认了双重抑制剂所具有类似抗抑郁药的性能，因此，利用多肽酶抑制剂改变内源性鸦片肽的浓度也许是有前途的治疗疼痛及慢性疼痛的新途径。
Modulation of the concentrations of peptide effectors has already been used successfully in the case of angiotensin-converting enzyme inhibitors and has preceded the clinical use of angiotensin II receptor antagonists.
Moreover, it is interesting to notice that repeated administration of high doses of acetorphan does not induce side effects, even in children . As reported several years ago, coadministration by the intrathecal route of thiorphan (NEP inhibitor) and bestatin (APN inhibitor) elicited potent, reproducible and long-lasting analgesia in cancer patients.
对多肽效应物质浓度的调制已经被成功地用于血管紧张素转换酶抑制剂的范例，并已领先于血管紧张素II受体拮抗剂的临床应用。另外，有意思地观察到，以重复大剂量的醋托酚施药并没有引发副作用，甚至在儿童身上。据多年前所报道，通过鞘内途径以赛奥芬（NEP抑制剂）和苯丁抑制素（APN抑制剂）同时投药可引起有效、可重现及持久的镇痛作用。
【英语牛人团】
Moreover, because of their higher intrinsic efficacy, enkephalins need to occupy fewer opioid receptors than morphine to give the same pharmacological responses Moreover, it has been demonstrated that inhaled NEP-inhibitor, thiorphan, failed to potentiate allergen-induced airway responses in asthma
此外，由于拥有较高的固有活性，脑啡肽比吗啡需要占用较少的鸦片受体就能给予相同的药理反应。而且已被证明，吸入脑啡肽酶抑制剂，赛奥芬，对于哮喘的过敏原诱发的气管反应效能没有增强。
The continued development of more effective and predictable methods for pain control is a process that combines the best efforts of basic and clinical scientists. Numerous studies have expanded the understanding of pain by focusing on the key role that receptors, signal transduction pathways, and genes play in mediating the response to inflammation or nerve injury. This has led to the identification of new targets for analgesic drug development. However, until now, the new strategies developed lead to drugs that are more active in animal models than in clinical trials , or are responsible of side effects.
持续发展更多行之有效及可预见性的疼痛控制方法，是将基础与临床科学家们殚精竭虑的成果组合一起的过程。许多研究把焦点集中于受体、信号转导途径和基因对炎症或神经损伤的介质反应的重要作用，对疼痛已有进一步的了解。这导致止痛药物的发展有了新的目标。然而，迄今新策略所发展出来的药物，在动物身上要比临床试验更有效或是有副作用。
Pain has traditionally been viewed as a pure sensory experience arising from physical injury or other pathology (cancer, diabetes, AIDS). However, it is now well accepted that psychological and behavioral factors play a key role in the chronic pain experience。 Thus, modifying the concentration of endogenous opioid peptides by use of peptidase inhibitors may be a promising new approach in the treatment of pain, and in chronic pain, owing to the antidepressant-like properties of the dual inhibitors recently confirmed with RB-101.
传统观念认为疼痛是身体受伤或其他病变（如癌症、糖尿病、艾滋病）所引起的一种纯粹的感官体验。不过，心理与行为因素对长期疼痛所发挥的重要作用如今已被广泛接受。鉴于最近通过RB-101确认了双重抑制剂所具有类似抗抑郁药的性能，因此，利用多肽酶抑制剂改变内源性鸦片肽的浓度也许是有前途的治疗疼痛及慢性疼痛的新途径。
Modulation of the concentrations of peptide effectors has already been used successfully in the case of angiotensin-converting enzyme inhibitors and has preceded the clinical use of angiotensin II receptor antagonists.
Moreover, it is interesting to notice that repeated administration of high doses of acetorphan does not induce side effects, even in children . As reported several years ago, coadministration by the intrathecal route of thiorphan (NEP inhibitor) and bestatin (APN inhibitor) elicited potent, reproducible and long-lasting analgesia in cancer patients.
对多肽效应物质浓度的调制已经被成功地用于血管紧张素转换酶抑制剂的范例，并已领先于血管紧张素II受体拮抗剂的临床应用。另外，有意思地观察到，以重复大剂量的醋托酚施药并没有引发副作用，甚至在儿童身上。据多年前所报道，通过鞘内途径以赛奥芬（NEP抑制剂）和苯丁抑制素（APN抑制剂）同时投药可引起有效、可重现及持久的镇痛作用。
【英语牛人团】