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生物英文论文翻译4A large fraction of the genes in Arabidopsis have a

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生物英文论文翻译4
A large fraction of the genes in Arabidopsis have antisense
transcripts (Borsani et al., 2005; Jen et al., 2005; Wang et al., 2005a;
Yamada et al., 2003). In most cases, these transcript pairs represent
neighboring, divergently transcribed protein-coding genes that
overlap for a region of their 3\2 ends. By contrast, the SPL3 antisense
transcript is nearly the same size as the sense transcript, it completely
encompasses the sense transcript and it does have significant coding
potential, suggesting that this transcript is dependent on sequencesthat are important for the expression of the sense transcript. Whether
this transcript plays a role in the expression of the sense transcript
remains to be determined.
The results of this and other (Schmid et al., 2003; Schwab et al.,
2005) studies indicate that SPL3 and the related genes, SPL4 and
SPL5, are under complex transcriptional and post-transcriptional
regulation. We are particularly intrigued by these three genes
because they establish a link between miRNAs and vegetative phase
change in Arabidopsis, and reveal that temporal variation in miRNA
expression plays a regulatory role in developmental timing in plants.
Further studies will be necessary to determine the precise
mechanism by which SPL3/4/5 expression is controlled during
vegetative and reproductive phase change, and the regulatory
pathways in which these genes operate.
We thank Manabu Yoshikawa for preliminary experiments that contributed to
the work described here, and to Stewart Gillmor for helpful comments on this
manuscript. ABRC and the FST project provided the T-DNA insertion lines used
in this study. This research was supported by a grant from the NIH to R.S.P.
大部份都反转录基因拟南芥(borsani等.2005年; 仁等.2005年; 王等.优先议程; 山田等.,2003).在大多数情况下,这些谈话对周边代表、 分歧转录蛋白质编码基因,它们的重叠区域为3结束.相比之下,反转录近spl3大小相同的意义全文,它完全涵盖全文,也有重大意义编码潜力 全文暗示这是很重要的依赖sequencesthat表达感成绩单.是否全文起着表达意识仍待定全文.这个结果和其他(Schmid等.,2003年; 施瓦布等.、 2005)研究表明spl3及相关基因,并spl5spl4,在复杂的转录和后转录调控.我们尤其大惑不解,因为这三个基因之间建立联系miRNAs与相变植物人 拟南芥、自然资源部透露,在表达时间变化起着调节作用植物发育时机.需进一步研究,以确定确切表达机制使spl3/4/5营养和生育控制在 相变,而这些基因的调节通路经营.我们感谢吉川灵活的初步实验工作,促成形容这里 为帮助和合演gillmor评论书稿.abrc和螺旋藻项目提供T-DNA插入线用于这项研究.这项研究得到了来自研究所赠款给r.s.p.