In spite of/ Despite 能否用在句子中间?

In spite of/ Despite 能否用在句子中间? In spite of and despite despite和in spite of in spite of 和 despite的区别? inspite,in spite,despite of,despite分别是什么意思?如何使用? in despite of和in spite of的区别? in spite of ,despite, regardless of的区别 despite of与in spite of又什么区别? Regardless of / in spite of Despite all the difficulties,we’ what are differences of despite and in spite of in spite of那么despite要加of吗 in spite of 跟 despite of的分别?