英语翻译As recently as 2002,most cases of primary membranous nep
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英语翻译
As recently as 2002,most cases of primary membranous nephropathy (MN),a relatively common cause of nephrotic syndrome in adults,were considered idiopathic.We now recognize that MN is an organ-specific autoimmune disease in which circulating autoantibodies bind to an intrinsic antigen on glomerular podocytes and form deposits of immune complexes in situ in the glomerular capillary walls.
As recently as 2002,most cases of primary membranous nephropathy (MN),a relatively common cause of nephrotic syndrome in adults,were considered idiopathic.We now recognize that MN is an organ-specific autoimmune disease in which circulating autoantibodies bind to an intrinsic antigen on glomerular podocytes and form deposits of immune complexes in situ in the glomerular capillary walls.
近至2002年,一种肾病综合症比较常见的病因,原发性膜性肾病(MN)- 大多数都被当作是不知原因的特发性来对待.如今,我们确认MN是一种器官特异性自身免疫病;这是由于循环的自身抗体结合肾小球足细胞的内在抗原,在肾小球毛细血管壁上沉积了免疫复合物所造成的.
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