作业帮英语翻译：这段文字什么意思？翻译这段文字
来源：学生作业帮 编辑：作业帮 分类：综合作业 时间：2024/05/24 05:42:29
英语翻译：这段文字什么意思？翻译这段文字
Understanding alternative splicing: towards a cellular code.
Matlin AJ1, Clark F, Smith CW.
Author information
Abstract
In violation of the 'one gene, one polypeptide' rule, alternative splicing allows individual genes to produce multiple protein isoforms - thereby playing a central part in generating complex proteomes. Alternative splicing also has a largely hidden function in quantitative gene control, by targeting RNAs for nonsense-mediated decay. Traditional gene-by-gene investigations of alternative splicing mechanisms are now being complemented by global approaches. These promise to reveal details of the nature and operation of cellular codes that are constituted by combinations of regulatory elements in pre-mRNA substrates and by cellular complements of splicing regulators, which together determine regulated splicing pathways.
Understanding alternative splicing: towards a cellular code.
Matlin AJ1, Clark F, Smith CW.
Author information
Abstract
In violation of the 'one gene, one polypeptide' rule, alternative splicing allows individual genes to produce multiple protein isoforms - thereby playing a central part in generating complex proteomes. Alternative splicing also has a largely hidden function in quantitative gene control, by targeting RNAs for nonsense-mediated decay. Traditional gene-by-gene investigations of alternative splicing mechanisms are now being complemented by global approaches. These promise to reveal details of the nature and operation of cellular codes that are constituted by combinations of regulatory elements in pre-mRNA substrates and by cellular complements of splicing regulators, which together determine regulated splicing pathways.
了解选择性剪接：对一个细胞的编码。
马特林aj1，克拉克F，史密斯CW。
作者信息
摘要
在“一个基因一个违反“规则，多肽，选择性剪接使单个基因产生多种蛋白质亚型-从而产生复杂的蛋白质中扮演一个重要的部分。选择性剪接也有隐藏的巨大功能基因靶向RNA定量控制，为无义介导的衰变。传统的基因的选择性剪接机制的基因正在由全球方法研究。这些承诺揭示的性质和细胞的代码，通过在mRNA前体的剪接调节底物和细胞补体调控元件组合构成的操作细节，它们共同决定调节剪接途径。
马特林aj1，克拉克F，史密斯CW。
作者信息
摘要
在“一个基因一个违反“规则，多肽，选择性剪接使单个基因产生多种蛋白质亚型-从而产生复杂的蛋白质中扮演一个重要的部分。选择性剪接也有隐藏的巨大功能基因靶向RNA定量控制，为无义介导的衰变。传统的基因的选择性剪接机制的基因正在由全球方法研究。这些承诺揭示的性质和细胞的代码，通过在mRNA前体的剪接调节底物和细胞补体调控元件组合构成的操作细节，它们共同决定调节剪接途径。