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英语高手帮我填个空There is a growing trend in the pharmaceutical indu

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英语高手帮我填个空
There is a growing trend in the pharmaceutical industry for large multinationals to use pan-European suppliers.( )has presented problems particularly for small and medium sized companies which produce in just one country.
选项:
A.These
B.This
C.That
答案:B.
has 单数排除A.
【这种趋势】已成为问题特别是对只在一个国家的中小型公司,指代前面句子表达的内容.排除C